An Out-Spoken Letter To The PuMie, TO WHOM THIS MAY CONCERN: It has been well said that better than great riches Is an established reputation for honesty and square dealing. In the long run no man ever loses anything by open, frank dealing--by taking his customers into his full con fidence. That Is the way I felt when I decided to take those who may be benefited by the use of my well-known medicines "Golden Medical Discovery" and "Favorite Prescription" which are to be found in every drug store of the land, into my full confidence and tell them just what ingredients enter into the oomposltion of these well-known medicines. I recall that In the practice of my chosen profession, I have often noticed that very many of my patients have wanted to know what I had prescribed for them to take It'is but natural that one should have some Interest In the composition of that which he Is expected to swallow. It is not unreasonable that we should have some regard for what we take into our stomachs, whether it be food, drink or medicine A BADGE OF HONESTY ON EACH BOTTLE. to conceal from the great majority of printing Reasoning along the above line and having nothing thousands who take my family medicines, and thinking that the my patients would proDaoiy like to Know what they are taxing, I am now on the wrapper or eacn Dottle or my mediomes tne ingredients or which it Is composed I feel that I oan afford to take my patients into my full confi dence, for my remedies contain nothing but such ingredients as have been ap proved and endorsed by the most eminent medical authorities men who have stood at the very head of the medical profession in this Sincerely. country. (SEE ENDORSEMENTS BELOW. This? mediotne Is a superior remedy for the ears Of all severe, chronic, or lingering' Coughs, Bron chitis Laryngitis, Weak Lungs, Bleeding from Lung's, pubUo speakers' Sore Throat, Hoarseness and Suppression or Loss of Voice. It does not nauseate, or debilitate the stomach or system, as other cough medicines do, but, on the contrary, Improves digestion, ctreng-thens the stomach, builds up solid flesh when reduoed below a healthy standard by disease, and Invigorates and cleanses the whole system. As a remedy for Torpor of the Liver (generally termed " Liver Complaint" or "Biliousness"), and for habitual ConaUpation of the Bowels, It has no equal. For loss of Appetite, Indigestion and Dyspepsia, and for General or Nervous Debility or Prostration, la either sex, It is a very superior medicine. As an alterative, or blood puri&or, this medicine is far superior to any preparation of sarsaparilla, iodide of potassium, or any other medicine now offered for general sale. It is, therefore, very val uablo in all forms of Sorofulous and other Blood Diseases; also for all Skin Diseases, Eruptions, Plmplea, Rashes, and Blotches. Boils, Ulcers, Sores, and Swellings, arising from Impure Blood, are oured by the use of a few bottles of this com pound. Unlike other Alteratives or blood-cleans-In? medicines, it does not debilitate, but strength ens the system. THIS IS A VERT CONCENT TBATED, VEGETABLE EZTSACT. The dose it mall and pleasant to the taste. FULL DIREC TIONS FOR ITS USE will be found In the pam phlet whioh is wrapped around each bottle IfASTOrACTURBD at tbb chemical laboratory of CTUD'S PIBPIKSaRT XISIOaL ASSOCIATION, ProiiliUrt, BUFFALO, 1ST. If. Endorsed by Leading Medical Writers. THE eick don't have to take Dr. Pierce's word alone as to the efficacy of his medicines, for every ingredient contained in thera has been extolled, over and over again, by leading medical writers. (See extracts below from several standard authors). Inas much as the people place confidence in Dr. Pierce and his medicines, there is nothing to fear from taking the public into his full confidence and frankly giving them the formula for his medicines, thus re ciprocating the confidence reposed in him. His patients may now know exact'y what they are swal lowing when they take these medicines. The ingre dients are printed, in plain English, on the wrapper of each boUle that leaves the great laboratory at Buffalo, N. V. This is a very unusual thing for a manufacturer of proprietary medicines to do. In fact, Dr. Pierce stands quite alone in this respect. Truth Is Mighty. SO many false formulas and malicious statement concerning his medicines have been published through the connivance of jealous competitors and disgruntled doctors, that he is determined to com pletely disarm his assailants by a full and frank state ment of their composition. He acts upon the belicl that "Truth is mighty and trust prevail," while fraud is a bubble that must soon burst. Medicines of Known Composition. IP suffering from an obstinate malady which would one naturally prefer to take, a medicine of known composition, every ingredient of which has the en dorsement of the most eminent medical practitioners and writers, ot one which, for aught you may know, maybe made up of very inefficient and even harmful agents? Is it not best to insist upon knowing what one is taking, as is every one's right, whether being prescribed for by the family physician or making use of a proprietary remedy ? We think so, especially in view of the very disparaging articles concerning vari ous advertised remedies with which the drug and medical journals have been filled for months past Dr. Pierce courts the severest criticism of the med ical profession as to the value of his published formula, confident that he will receive fair treatment from all fair-minded, well qualified brethera of the medical profession who cannot be blamed for not endorsing medicines of the composition of which they and the people are kept in ignorance. No Alcohol Used. DR. PIERCE never believed it necessary or advis able to use alcohol in the preparation of either his "Favorite Prescription" for weak women, or his Golden Medical Discovery," the well-known altera tive tonic, which is so largely used as a remedy for indigestion, torpid liver, bad blood and kindred ailments. Over forty years ago, he discovered that chemically pure glycerine is a far better solvent of most of the active principles residing in our native medicinal plants, when used at a proper and sus tained temperature, than is alcohol; and, furthermore, he found that a glyceric extract kept much better than an alcoholic one, and that the glycerine pos sessed intrinsic remedial value, being demulcent, nutritive and an effective anti-ferment. Although costing somewhat more, Doctor Pierce predicts that glycerine medicinal extracts will, in the not distant future, largely replace alcoholic ones so generally prescribed by physicians and pit out by proprie tary or "patent medicine " manufacturers, as being more efficient and entirely free from the serious objection of making inebriates when used in lingering or chronic cases, where a somewhat protracted use of medicine is necessary, no matter how good or well adapted to the case it may be, in order to ob tain permanent results. pilpHs: . . .- .f mm Suit?) XV&t v m km jmppmm nnlfhnrw renews- ifodisXass n m - - -.-..1 Ask Your Family Physician IF a medicine scientifically prepared from just the right proportion of each of the following ingredients must not in proper doses be a splendid tonic, restorative and nervine for weak, nervous, worn-out women. If he is an honest, fair-minded man, well up in his profession, and not given to extreme jealousy, he will answer in the affirmative. The ingredients are : Blue Cohosh root, Unicorn root, Golden Seal root, Black Cohosh root, Lady's Slipper root and chemically pure Glycerine of proper specific gravity. These are the ingredients, combined in just the right proportions, from which, with proper apparatus and appliances, Dr. Pierce makes a non-alcoholic glyceric extract, working after a process which cost him and his collaborating chemists and pharmacists a long time study and a tedious and painstaking course of experiments, be fore he was able to produce, in satisfactory perfec ' tion, the two leading medicines which bear his name and which are generally acknowledged to be elegant pharmaceutical compounds. A Weak, Ailing Woman OR an invalided man, don't need to take Doctor Pierce's word alone as to the remedial virtues of his medicines. To any one writing Dr. Pierce at Buffalo, N. Y., care of Invalids' Hotel, he will take great pleasure in mailing a little book of extracts made up from the standard medical books of the day, giving the most trustworthy endorsement of the several ingredients used in making his medicines. No words of ours could possibly extol these virtues to exceed the language used in these numerous ref erences. On account of lack of space, we can only print, below on this page, a few brief extracts from standard writers on Materia Medica, to show that the ingredi ents of which Dr. Pierce's Golden Medical Discovery and Dr. Pierce's Favorite Prescription are composed, are to-day acknowledged by all schools of medicine, to be the most valuable remedial agents known for the several diseases for which we recommend these medicines. Forty years ago, when Dr. Pierce began the use of these several ingredients in his daily prac tice many of them were little known to medical practitioners in general. As an indication how some of them have grown in use and professional favor since that time, we note that Golden Seal root, which could then be bought in the open market at from fifteen to twenty-five cents a pound, is to-day worth upwards of one dollar and fifty cents a pound. Lady's Slipper root (" American Valerian ") has also advanced greatly in professional favor, and is to-day prescribed by the most advanced physicians to such an extent as to have caused its market value to quadruple. We point to these significant facts as confirmatory of Dr. Pierce's good judgement in selecting the com ponent ingredients, of which he makes his now wide-renowned remedies. Read What Others Say of the ingredients of Dr. Pierce's medicines in the columns below and you must be convinced of their exceptional value and curative potency. The author ities quoted are standard in their several schools of medicine as any well-read physician will recognize. World's Dispensary Medical Association, World's Dispensary and Invalids' Hotel, Buffalo, N. Y. Ours Not a Gift Enterprise. WE send no free, give away, or "trial " bottles for experimental work. Our medicines have a well established value, can be had at all medicine stores at reasonable prices, are of known composition and well attested curative potency. Vou don't ex periment with your case when you employ them for any of the easily recognized ailments for which we recommend them. World's Dispensary Medical Association, Proprietors, Buffalo, N. Y. lortlie cure of those AND FtfIX DIRECTIONS for using this medicine, also history and symptoms of numerous eases and form I oj disease for which, it is especially i adapted, may be found in the inclosed pamphlet. Rflfiatpreri an a. Trademark and aa a T.hl. In w :"s.7 u. s. i'L uinee. dmv juui. iot. t: snr.i4 -la yV . -- VJ7 Medical Authorities Endorse and Extol the Ingredients of which Dr. Pierce's Two Leading Remedies are Composed. IIP WORDS OP PRAISE FOR INGREDIENTS OF DR. PIERCE'S GOLDEN MEDICAL DISCOVERY From Eminent Medical Writers, Dr. Bartroi.ow, a recognized authority on Materia Medica and Therapeutics, says of Hydrastis (Golden Seal): "Very useful as a stomachic tonic (stomach tonic) and in atonic dyspepsia. Cures gastric catarrh (catarrh of stomach) and headaches accompanying same. In catarrh of the gall duct and jaundice, it is of especial utility. Constipation, dependent upon different de ficient secretions, with hard and dry stools, may be ivreimm , Vi rt ri . d . Phrnnif. catarrh r( t Vi inttm Muty utriicuLcu uj xiyutasiin. 111 unsure ui luc auua, hemorrhage (bleeding) from the rectum, and ulceration of the rectal mucous membrane, hydrastis produces 3sVfir viv-Trvy I healing. It may be given as a remedy for intermittent, "TjfVSJ 7IV I chronic and malarial poisoning, and enlarged spleen of uiaiiiuai uiiKUi. n lessen, luc buviciluu ui niuuiu ill m chronic Bright' disease, diminishes mucus in catarrh -of the bladder. It may be expected to do much good in cases of paresis and paralysis, when the lesions causing them are not of recent origin ; also in paralysis suc ceeding fevers and other acute diseases. Valuable in uterine hemorrhage, menorrhagia and congestive dys menorrhea. Locally good in uterine and vaginal leucor rhiea, ulceration and erosion of the cervix, unhealthy and sloughing sores and old ulcers of the leg." The foregoing is certainly a wonderfully strong en dorsement of one of Dr. Pierce's chief ingredients used in " Golden Medical Discovery," and also in his "Favorite Prescription." From "Organic Medicines," by G ROVER Cok, M. D., of New York, we extract the following : "Hydrastis (Golden Seal) exercises an especial influence over mucous sur fucrt. Its action in this respect is so manifest that the indications for its employment cannot be mistaken. Upon the liver it acts with equal certainty and efficacy. Ai a cuologogue (liver invigorator), it has few equals. In affectious of the spleeu, and abdominal viscera generally, it is an efficient and reliable remedy. Also iu scrofula, glandular diseases generally, cutaneous eruptions, indi gestion, debility, diarrhaa and dysentery, constipation, piles and all morbid and critical discharges." Dr. Cos continues: "Hydrastis (Golden Seal), has been successfully employed in the cure of leucorrhcea. It is of singular efficacy When that complaint is com plicated with hepatic (liver) aberration (derangement). Hydrastis is also of inestimable value in the treatment of chronic derangements of the liver and portal circulation. It seems to exercise an especial influence over the portal vein end hepatic (liver) structure generally, resolving (diSHolving) biliary deposits, removing obstructions, pro moting secretion, and giving tone to the various func tions. It h eminently cholagorue (liver accelerator), nnd may be relied upon with confidence for the relief of hepatic (liver) torpor." "In many deraneements of the urinary apparatus we have found the Hydrastis to answer an admirable pur pose. In chronic inflammation of the bladder, we deem it one of the most reliable agents of cure. As a tonic in the convalescing- staees of fevers, nnrumnmi clvmT.trrv. and other acute diseases, particularly when a laxative property Is needed, the Hydrastis Is peculiarly appropriate. It promotes digestiou and assim ilation, obviates constipation, and gives tone to the depurating functions generally." Dr. Cob continues: "We would here add that our experience has demonstrated the Hydrastis to be a valuable remedy in bronchitis, laryngitis, and other auections of the respi ratory organs-" After reading the foregoing extract who can doubt the great efficacy, in a long list of dis eases, of "Golden Medical Discovery " one of the principal ingredients of which is Golden Seal (Hydrastis)? BLACK CHERflYBAItlC (Prunua Virginians). '' ROBERT BathoIX)W says: "Wild Cherrybark is su excellent stomach tonic i it ha long en held in great esteem in dometic practice, a a remedy in catarrhal states of the bronchial ucous membrane and in Phtbiais (Consumption)." "The tirup is much used as an ingredient permanently cures bronchitis relieves irritations an important Bern may cough remedy coughs of years standing ired. Aids in blood-making and nuti taken without harm for long periods." MANDRAKE (Podophyllum). Certain, sure cathartic ; leave bowels in improved condition. A gentle stimulant tonic ; improves the appe tite. Particularly valuable in dyspepsia, gastric aud intestinal catarrh. Beneficial in some affections of bladder. DLOODROOT (Sangulnaria). Stimulates digestive organs, increases action of heart and arteries stimulant and tonic. Very valuable as a cough remedy acts as a sedative further valuable as alterative. STONE ROOT (Colllnaonlo Canadensis). Alterative, tonic, stimulant. Valuable in laryngitis "Ministers sore throat." In diseases of stomach and in testines improves appetite, promotes flow of gastric juice: tonic effect upon organs involved. A good remedy in indigestion, dyspepsia, chronic gastritis, in creasing the secretion from kidneys and skin. The foregoing four, several extracts are all taken from the American Dispensatory, by Professors Kino and Scudder. Prof. Wm. Paine, M. P., of the old Philadelphia University of Medicine and Surgery, in his work en tiled "The Medical Properties and Uses of Concentrated Medicines," writing of Collinsonin (the active medicinal principle residing in Collinaonia Canadensis, or Stone root), says: "I, not long since, had a patient who was so much oppressed with a valvular disease of the heart that his friends were obliged to carry him up-stairs. He, however, gradually recovered under the inlluence of Col linsoniu, and is now attending to his business. Hereto fore physicians knew of r.o remedy for the removal of so distressing and so dangerous a malady. With them it was all guess-work, and it fearfully warned the afflicted that death was near at hand. Collinsonin unquestion ably affords relief in such cases, a id in most instances effects a cure." He further says : " Iu a case of persistent ascites (dropsy), where the ordinary remedies fail to af ford anything more than a temporary relief, Collinsonin produced a permanent cure." Prof. John M. Scxdder, M. D., in his treatise entitled "Specific Medication," says: "Collinsonia (stone root), is a specific in 'ministers' sore throat' (chronic laryn gitis)." He continues: "It proves beneficial in other cases of chronic laryngitis, in chronic bronchitis and phthisis (consumption), allaying irritation and check ing cough. It also exerts a favorable influence upon the digestive processes, improving the appetite, facilitating digestion and acting jis a general tonic. It passes off through the kidneys and exerts a tonic influence upon the entire extent of the urinary tract I regard it as one of the most direct and valuable agents of the Materia Medica and one that will give saiisaction to uhotver tmftloys it." The above are stronjj endorsements of one of the most valuable ingredient i contained in "Golden Medical Dis covery," viz., Collinsonia, or stone root. Its virtues how ever are r.ot over-c.-tolled, as we can attest from our experience and observation in watching the beneficial action of the "Discovery "io heart affections, laryngitis, bronchitis, incipient consumption and other ailments noted above. be raucous in cough mixtures." QUEEN'S ROOT (Stlllln3U). Prof. JOHM Kino, M. D., say : "An alterative unsurpassed by few if any other of the knows alterative at aucrcifiu la akin aud suofulouA aflcctimi. Bene final ia bronchial affections WORDS OFPRMSE FOR INGREDIENTS OF Dr. Pierce's Favorite Prescription from welt recognized authorlflem of all Schoolm ot Medicine, What Edwin M. Hale. M. V ,' Professor Materia Vedica, at Hahnemann Medical College, Chicago, ay : "Among the earliest medical writer of thi country was Prol. JUriNKaQua, a ecieuune botanist aaA nj scholar. He thus writes of Hydrastis (Golden Seal), ' Internally, it is used as a bitter tonic in disorders of the stomach, liver, etc.' " Dr. Hale continues : "Howard, writing in 1836, says: 'It is very useful in recovery from fever, for dyspepsia, indigestion, sore eyes, ulcers, loss of appetite, etc.' 1 "Dr. Barton and Dr. Tully estimated it very highly as a ' pure tonic, and as an alterative iu diseased condi tions of the mucous membranes.'" "Prof. John King, M. D., gives it a prominent place among medicinal agents ; reiterates all that previous writers have said about it, and adds that it is valuable in 'chronic affections of the mucous membrane of the stomach, intestines, bladder, etc' " Dr. Hale continues: "Prof. John M. Scudder says, 'It stimulates the digestive processes, and increases the assimilation of food. By these means the blood is en riched, and this blood feeds the muscular system.' ' I mention the muscular system because I believe it first feels the increased power imparted by the stimulation of increased nutrition. The consequent improvement on the nervous and glandular systems are natural results.' 'In relation to its general effects on the system, there is no medicine in use about which there is such general unanimity of opinion. It is universally regarded as the tonic useful in all debilitated b tales.'" BLUE COHOSH (Cautophyllum). Of Caulophyllura (Blue Cohosh), Rafinesque states that : "As a powerful emmenaogue it promotes men struation and dropsical discharges," and that "It was employed by the Indians for rheumatism, dropsy, epilepsy, hysterics, inflammation of the uterus, etc." I'rof. King first employed Blue Cohosh for its beneficial influence on abnormities of the mucous tissues, using it for aphthous stomatitis (sore mouth), in decoction, alone or combined with Hydrastis (Golden Seal). Prof. Scudder believed that this agent exerted its influence through the hypogastric plexus (of nerves), thus affecting the circulation, nutrition and functions of the repro ductive apparatus. The American Dispensatory says : " Blue Cohosh is emmenagogue, and its use as a partu rifacient originated in the custom of the Indian squaws of employing a decoction of the root for two or three weeks previous to labor to facilitate child-birth." I'rof. John Kino, M. D., says: " As s partus prtrpar. ator. Blue Cohosh has enjoyed a well-merited repu tation. When used by delicate women, or those who experience prolonged and painful labors, for several weeks previous to confinement, it gives tone aud vigor to all the parts engaged in tue accouchement, facilitating its progress, and relieinng much suffering." Prof Hale testifies that women who have taken Caulophyllum previous to confinement, have over-run their time from ten to twelve days, but all had very easy labors and made good recoveries. Blue Cohosh acts as an anti abortive by relieving the irritation npon which the tiouble depends. Kino states that for this purpose it is fully equal to viburnum. He continues, "It has been employed to relieve irritation of the reproductive organs dependent on congestion. It controls chronic inflammatory state of the organ and give tone in cases of debility. In the sexual disorders of the femaie it is indicated by tenderness and pain in the uterus. In de bilitated patients, it has been very successfully used in cases of hysteria to overcome the attack, and to relieve ovarian, or mammary pain, or irritation when accom- Jianying that disorder. Chronic ovaralgia, uterine eucorrha-a, amenorrhea (suppressed menstruation ) and dysmenorrhcea painful menstruation), are conditions in which it has been most successfully employed. It has an established reputation as a remedy for rheumatism of the uterus, with nervous excitement, for uterine cramps attending menstruation, and for menorrhagia "flooding. UNICORN ROOT (Chamalirlum). The American Dispensatory (prepared by Professors Kino and Scvddf.b), says: "He Ionian, or Unicorn root, has been found very beneficial in dyspepsia, loss of appetite, and for the removal of worms. It is more especially applicable in indigestion, dyspepsia and mal assimilation, where the trouble is reflex from, or asso ciated with, wronis of the female reproductive appar atus. Such digestive) disturbances as depend upoa uterine and ovarian irritation, or npon lack of uterine activity, in chlorotie anemia, are benefited by it It is valuable in atony (weakness) of the generative organs." Prof. Kino says, "have found this plant to possess a decidedly benefical influence in cases of sexual lassitude in both sexes, the result of excesses, especially in those instances where there are symptoms of gastric (stomach) derangement with impaired memory, mental apathy, or indifference, and an enfeebled condition of the general system, with weakness or dull pain in the renal, or lumbo-sacral ('small of the back ) region. In diseases of the reproductive organs of females, and especially of the uterus (womb), it is one of our most valuable agents, acting as a uterine tonic, and gradually removing ab normal conditions, while at the same time it imparts tone and vigor to the reproductive organs. Hence, it is much used in leucorrhara, amenorrhaea, dysmenorrhcea and to remove the tendency to repeated and successive miscarriages. A particular phase removed by it is the irritability and despondency that often attends uterine troubles. In painful menstruation it has been found especially adapted to those cases in which there is pelvic fullness, a sensation as if the womb and rectum were distended with blood, and the aching, bearing down organs feel as if they would fall out of the body. Its action here is very decided. It is considered use Ail by some for the relief of the vomiting of pregnancy, Helonias is a decided tonic, to the urinary tract," BLACK COHOSH. (Clmiclluga Racamosa, SquawrooL Elo.) Prof. John Kino, in the American Dispensatory says: "This is a very active, powerful and useful remedy, and appears to fulfill a great number of indications, It pos sesses an undoubted influence over the nervous system. In small doses the appetite and digestion are improved." He continues, " Upon the reproductive organs it exerts a specific influence, promoting the menstrual discharge." "Macrotys (Black Cohosh) plays a very important part in the therapeutics of Gynecology (diseases of women). In the painful conditions incident to imperfect menstrua tion, its remedial action i fully displayed. By its spe cial affinity for the female reproductive organs, it is an efficient agent for the restoration of suppressed menses. In dysmenorrhea (painful periods), it is surpassed by no other drug, being of greatest utility in irritative and congestive conditions of the uterus and appendages, characterized by tensive, dragging pains, resembling the 1 pains of rheumatism. It is a good remedy for the reflex side-aches' of the unmarried woman. It should be re membered in rheumatism of the uteru, and in uterine leucorrhea. When there is a disordered action or lack of functional power in the uterus, giving rise to sterility, cimicifuga (Black Cohosh) often corrects the impaired condition and cures, Keflex mammary pains during ges tation are met by it, and in rheumatic subjects it promptly relieves such ovarian troubles as ovaralgia and neural gia. Its action is slow, but its effects are permanent. It has been used successfully as n antispasmodic in hys teria, epilepsy when due to menstrual failings, periodical convulsions, nervous excitability, and many other spas modic a fleet ions." For headache, whether congestive or from cold, neur algia, dysmenorrhcea, or from la grippe, it is promptly curative. As a remedy for pain, macrotys is a very prompt agent often relieving in a few hours, painful con ditions that have existed tor a long time.- LAOVS SLIPPER ROOT (Cyprf podium). Prof. John M. Scudder says : "This root is valuable in all cases of nervous excitability or irritability unconnected with organic lesions, allaying the irritability, lessening sny sccora panyisg pain, producing a more calm and cheerful condition of the body and mind, and con sequently favoring mental tranquillity, or sleep. Hence it has been of service in hysteria, chorea, nervous headache, wakefulness and prostration in low fevers, epilepsy from reflex irritation, and, indeed, in all cases of morbid irritability of the nervous system, txorn functions! derangement or reflex irritation. It will be found very efficient in the nervousness, hypoc hondria, or mental depression accompanying certssln forms of derangement of the digetive organs, which is more generally met with among females." The foregoing are only a few brief extracts taken from amongst the voluminous endorsements which the several ingredients entering into Dr. Pierce's Favorite Prescription have received from the most eminent medical writers of all the different schools of medicine. After reading them can any reasonable person doubt that Dr. Pierce has selected and compounded his "Prescrip tion " from the most valuable ingredients known to the medical profession for the cure of those ckrenia diseases of women for which he recoaaujuU it 1 ITS! IUKS